Precirol® ATO 5 is a multifunctional excipient: a sustained release agent, lubricant and a taste masking agent for oral dosage forms.
Used at levels of 10% to 20% for the development of tablets, it forms an inert matrix which, 'in vivo', slowly releases the active through erosion/diffusion. Used between 3% to 20% in a coating processes, such as hot melt coating (Gattecoat® process), the coated drug molecules can be formulated with other ingredients and then compressed in to tablets with sustained release properties.