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Sustained Release Agent

Name Gelucire® 50/13
Chemical Name Stearoyl Macrogolglycerides (Polyoxylglycerides)
Physical Appearance Waxy Solid Pellets
Melting Point 50 C
HLB 13
Regulatory Status USFA, EP, USP-NF, FDA IIG
Description Gelucire® 50/13 is a semi-solid excipient that is proven to improve the bioavailability of poorly soluble drugs.

Gelucire® 50/13 can be used in a variety of formulation techniques (granules and tablets) and it remains an excipient of choice for formulation in capsules.  Formulated in capsule Gelucire® 50/13 will confer a slow release profile due to its high drop point.

When used in granulation or other combined approaches, it delivers an immediate release profile due to its high HLB.

 


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